1. Introduction

a) The brain imaging platform, managed by the Tsinghua Laboratory of Brain and Intelligence, the facility has two high-performance magnetic resonance imaging systems, Siemens 3.0 T MAGNETOM Prisma and Bruker 9.4 T high-field small-animal horizontal-axis magnetic resonance imaging system (Bruker BioSpec 94/30USR). The former is used for research in human brain science and clinical applications, while the latter is used for research in brain science and biomedical experiments on several experimental animals.

b) Siemens 3.0 T MAGNETOM Prisma Scanner is a high-end MRI system capable of non-invasive imaging of all parts of the body with high resolution and a high signal-to-noise ratio. It has a wide range of applications in clinical diagnostics and scientific research and is especially good at brain functional imaging. It can perform sub-millimeter high-definition brain functional imaging, which can help to promote the study of brain cognitive mechanisms. Its gradient field strength and gradient switching rate can reach 80mT/m and 200mT/m/s, respectively, which can help realize 2mm high-definition diffusion imaging, discover tiny lesions, and realize early and accurate diagnosis. Prisma's high-gradient system and TrueShape RF scientific research platform enable it to realize sub-millimeter high-definition brain functional imaging, which is crucial for accurate diagnosis and research on the activities of the brain's functional areas. Prisma is capable of performing high signal-to-noise ratio fMRI, which is useful for studying changes in brain activity during specific tasks, such as cognitive, emotional, sensory, and motor functions. Prisma's high-gradient performance enables high-resolution diffusion imaging, which is invaluable for studying the microstructure and connectivity of the brain's white matter fibers. Prisma's high resolution and high signal-to-noise imaging capabilities make it an ideal tool for studying brain networks and connectomics, which is important for understanding how the brain coordinates activity between different regions. Prisma plays an important role in the study of neurodegenerative disorders such as mild cognitive impairment (MCI) and Alzheimer's disease, which can help in the early diagnosis and monitoring of the disease's progression. Prisma is capable of combining multiple imaging techniques such as structural imaging, functional imaging, and spectral analysis to provide comprehensive data for brain science research.

c) The Bruker 9.4T High Field Small Animal Horizontal Axis Magnetic Resonance Imaging System (Bruker BioSpec 94/30USR) is a high field strength MRI system designed for preclinical research, which offers significant advantages in many medical and scientific fields. The system provides high-resolution imaging down to the micron scale, which is particularly important for studying fine structural changes in small animal models. Suitable for a wide range of laboratory animals, including mice, rats, and small primates, it allows structural, functional, and metabolic imaging as well as spectral analysis. Equipped with a high-performance gradient system featuring high gradient strength and rapid switching rates, it facilitates rapid imaging and enhances image quality. In research fields such as oncology, neurology, cardiology, and infectious diseases, it offers high spatial and temporal resolution applications. In the realm of brain science research, it can perform micron-scale imaging of brain structure and multi-parameter imaging of brain function, contributing to breakthroughs in core neuroscience issues such as language, emotion, social interaction, and decision-making.  As an open platform, it serves units and researchers engaged in brain science, biomedical science, and other fields both within and outside the university. These advantages make the Bruker BioSpec 94/30USR an advanced tool bridging modern medicine and preclinical research imaging, providing robust support for life sciences and medical research.

2. Technical Staff

Yang Cong
Magnetic Resonance Imaging Technician

Zhu Xiaofeng
Magnetic Resonance Imaging Technician